Non sedating anti emetic

29-Dec-2016 16:28

The present invention will be further illustrated with reference to the following Example. Catherine's Hospice were given various anti-emetics to control nausea and vomiting of various aetiologies. In 16 (69%) of the 23 methotrimeprazine patients with intractable nausea and vomiting (largely unresponsive to a number of anti-emetic drugs) symptom control was achieved. For parenteral administration the dosage will be up to 10 mg per day for delivery intravenously, intramuscularly or by subcutaneous injection, or up to 12.5 mg per day for delivery by continuous subcutaneous infusion, for example using a syringe driver. In this study, the absence of symptoms or the reduction of symptoms to a level that was acceptable to, or tolerated by, the patient without causing side effects was considered to demonstrate the control of nausea and vomiting.A non-sedating anti-emetic composition in oral unit dosage form comprising from 1 to 5 mg of methotrimeprazine per unit dosage, or in unit dosage form for parenteral administration comprising from 1 to 5 mg of methotrimeprazine in each unit dosage.

A non-sedating anti-emetic composition in oral unit dosage form comprising from 1 to 5 mg of methotrimeprazine per unit dosage, or in unit dosage form for parenteral administration comprising from 1 to 5 mg of methotrimeprazine in each unit dosage....The choice involves balancing the need for quick pain relief with other treatment considerations as well as convenience and personal preference.Many people find oral medicines the most convenient to take, as well as the most portable.Also, nausea and vomiting during a migraine attack can seriously interfere with the effectiveness of oral medications.Oral medications are a good choice for people who have tension-type headache, migraine without nausea and vomiting, or migraine attacks that come on slowly, allowing early treatment.

A non-sedating anti-emetic composition in oral unit dosage form comprising from 1 to 5 mg of methotrimeprazine per unit dosage, or in unit dosage form for parenteral administration comprising from 1 to 5 mg of methotrimeprazine in each unit dosage....The choice involves balancing the need for quick pain relief with other treatment considerations as well as convenience and personal preference.Many people find oral medicines the most convenient to take, as well as the most portable.Also, nausea and vomiting during a migraine attack can seriously interfere with the effectiveness of oral medications.Oral medications are a good choice for people who have tension-type headache, migraine without nausea and vomiting, or migraine attacks that come on slowly, allowing early treatment.Nasal sprays enter the bloodstream more quickly by being absorbed through the membrane lining the nose.